Everything is very originally perfect: The patient that makes a person use a facial expression pours out the endless anguish that —— disease brings, life glorious does it bleak, however, the occurrence of new drug changed everything, the life is on the right path afresh. The enterprise that vow solemnly is enunciative —— is a center with the patient, make conscience drug hard. Do not wear the expert of the trace echoes sb this disease needs —— early discovery early treatment, early one day uses this drug, the effect is big different.
Ask about till somebody: "How many money does this medicine get? "How many money does this medicine get??
The expert appears not alert, answer immediately: "7900 yuan... " did not wait for him to say, company controller crosses line of thread of discourse with respect to cut: "We measure the social value of a product very hard from the price, the change that should see it brings a patient the life... " but, somebody has been in whisper: "This price is too high! How many person is hit? How many person is hit??
This is Ai Baiwei of tycoon of international medicine look forward to the one act on the press conference that to popularize its product Xiu Meile holds. Recently, xiu Meile is approved by supervisory management board of Chinese food medicines anfree watch cased chemical reagents, use at treating rigidity sex rachitis. Ai Baiwei had typical medical sale activity one round for this. Include to establish among them " the handvancouver to harrison hot springs is grasped tomorrow " commonweal project. Nevertheless, in these activities, the price is sensitive topic forever, be worn by cautiously oversight. They talk about dream, hope and responsibility gladlier.
In fact, not only Ai Baiwei is such, almost look forward to of all foreign capital medicine are sedulous when releasing new drug evasive price issue. In for its product luck answer beauty (the new drug that cure delivers sexual marrow tumour more) those who hold appear on the market on the news briefing, the United States is new base company option is opposite directly the reporter is turned a deaf ear to about the query of the price. When enquiring with the form of mail when the reporter this medicine creates how old economy burden to the patient after all again, they remain the same turn a blind eye to. Nevertheless, they also admit " the expenditure of the cancer innovation therapeutics of nowadays is very tall " .
Too costly, this is the reason that these medical look forward to do not wish to allude publicly. The United States " Forbes " Ceng Lie crosses sheet of a list of names posted up, the single remedy with the top price on the world is Soliris, use at cure clonic Morpheus sex haemoglobin make water, annual remedial fee is as high as 410 thousand dollar actually. However, record subsequently by refresh. Last year the end of the year, EMA of orgnaization of European medicine inspect approves a kind of gene that is called Glybera formally to treat medicaments, use at treating lipoprotein of a kind of extremely infrequent transmissibility disease —— lipase lacks disease (LPLD) , its charge reachs the 1.6 million dollar of unprecedented. Although common new drug is not such hyperbole, but if long beauty is happy such at every turn thousawatch case openernds of on 10 thousand yuan price or common see.
Depending on high price just about, pharmacy estate magnate grabbedthe most popular watch cases amazing sudden huge profits. Accordingly, they always are the frequenter of 500 strong companies of world, its steady growth makes more other industry is envied unceasingly. " magazine of new england medicine " before Xi Ya of chief editor Ma·Angell discovers amazedly, 2002, the total of profit of 10 pharmacy company in 500 strong list can exceed other the profit total of 490 enterprises.
"Pharmacy cause is true make money, imagine pharmacy company has how many money after all very hard. " she can'ts help sighing with emotion.
The reason of high profitbrass faucet
Why is pharmacy line of business OK the profit that will help medicine decides such high price and get astonishment making a person? Their answer can be the beautiful story of an industry normally. This story includes two content normally: The social value that figure of cost of a string of research and development and medicaments bring.
New base the company stresses such fact: Be in the United States, the amount of the person thwatch case manufacturerat 20 years the cancer of a pharmacy trade minister lived in the past grew 1 times, arrive from 7 million growth 14 million. "Adopt our method, we helped a lot of cancer patients enter the disease state that can run for a long time, and obtain cure " ; " tumour of the much marrow that send a gender, go 10 years, the patient's survival rate rose 73% . Previously, because medical treatment level is finite, the fund that patient of myeloma of the much bone that send a gender calculates the flower is again much also cannot receive treatment, cannot live longer, more high quality ground lives. More high quality ground lives..
Subsequently, new base the company shows, all these does not come in vain, pharmacy line of business gives the time with the exploration long —— of hardships and countless money for this. "An innovation therapeutics arrives to make the patient is benefited finally from research and development the time that needs 15 years. There is 1 kind to be able to pass clinical trial only in 10 thousand kinds of compound, there is 1 kind only in 10 kinds of therapeutics but the meaning of gain. There is 1 kind only in 10 kinds of therapeutics but the meaning of gain..
Wei Saile of the president before Nuohuaji is round ever had written Switzerland to be called originally " magical anticarcinogen bolus " book. In the book, his row counted ongoing hair Glenn to defend (a kind of target that treats leukaemia to medicaments) in course, if why Nuo China thinks for the first with the patient, ignore prospect not the risk of beautiful, ecbolic the fact of new drug. Nevertheless, the price —— that he is clear about to Glenn is defended is chronic period patient of leukaemia of sex of chronic bead cell is daily the remedial charge of 400 milligram is dosage every months 2000~2400 dollar, quickly period or acute is changed period patient of leukaemia of sex of chronic bead cell is daily the remedial charge of 600 milligram is dosage every months the censure that place of 3500 dollars —— causes.
"We agree with those thinking that Glenn defends the opinion with quite high price really, be in however after measuring all elements and condition, we believe firmly this price fairness is reasonable. " marrow of variant of the —— after the cost when comparing a patient to choose other treatment plan transplants 193 thousand yuan and complication probability is high, the cost that influences cure of cure, interferon and Glenn are defended identical and side effect is very big he expresses —— so.
Of Wei Saile still have apologetically: If the place before new drug appears on the market each phase of exercise include a consideration, the plan project that estimates each new drug must expend 600 million dollar. Before be being worn on new drug, the Cheng when needing is average take time 10~14 year. "It is 20 years only in view of patent length of protection, because this remains 6~10 only year gain period, in this inside gain period, we must earn sufficient profit, will pay foregoing capital and risk investment, and undertake what enterprise reinvest needs funds. If lost patent safeguard, criterion the advantage that product value will not gain profit. Unavailable expectant profit, can no more the research and development of invest in follow-up. This matter has nothing to do morality, also have nothing to do dispute, it is the logical question that the industry survives purely " .
Line of business of pharmacy of recognize of community of his expectation society is on some kind of angle " also be business already battalion, with Microsoft, General Electric Company or different of that's all right of company of 100 things coke. We hope to borrow likewise by sell a product and get profit. Without benefit embellish won't have fund, won't have research and development, won't have investment, in the end won't have new product. A lot of people often oversight this be related is solid, and the footing that would rather stand in nearsightedness, want to buy drug with fewer money only. Want to buy drug with fewer money only..
His succession person Jiang Muzhong also holds similar point of view when accepting a reporter to interview. Jiang Muzhong says, "Wthe best spring poole must obtain enough earnings ability to undertake reinvest of research and development, so that develop the innovation medicaments of new generation " .
Such, high price and huge profit are manage place it seems that ought to.
Took what ought not to take
However, is the price with new high drug to cover cost of research and development and promotive adventure innovation only really? Existing evidence shows —— is not completely.
Recently, another crosses arrowroot of tycoon of look forward to of traditional Chinese medicine gram of Lan Su hithe best selling modern dining chairsstory was immersed in a trouble in China. Public security body says, be in China during managing, open sale channel of medicines and chemical reagents to achieve, raise the goal such as drug price, its wait to guild of medicine of official of individual government sector, minority and foundation, hospital, doctor wantonly bribery. "This case involves personnel much, duration is long, experience record amount is huge, guilty clue is abominable. Guilty clue is abominable..
Liang Hong of vice president of division of Shi Kezhong state explains the Ge Lan element that investigates according to be being taken away to accept by police, the proportion that operation of medical look forward to holds in medical price is as high as 20% ～ 30% . On bribery chain, go up to wait for function branch to company of industrial and commercial, prices, person, hospital of Chinese basic level, doctor comes below. Some sells brushstroke of settle accounts of a batch of medicine fund, cooperative doctor sends credit card each, after opening medicine, make sales commission into Zhang the following day. Of course, this all charge bury sheet finally by the patient.
After its, asilikang's employee also is taken away by police.
norton internet antivirusThis makes Chinese public big open horizon. Although before each old drug look forward to is in the United States repeatedly because of " undeserved pay " and suffer punish again, and venue is in China more, but in China they are avoided from beginning to end at finding out. Also did not happen like what thing. Door of bribery of Shi Ke of arrowroot orchid element tore eventually golden body.
Actually, euramerican media undertakes passing a system to medical look forward to disclose and critically. Maxiya·Angell ever wrote this book technically " the truth of pharmacy line of business " . In the book, she points out: "Medicaments price is not decided by place of cost of its research and development. Contrary, by them the value in pharrison hot spring public poolrecaution and remedial disease decides it. This word listens in me come, it is he admitted this industry is met ground of do one's best decides the value as far as possible tall, and this price follows cost of research and development concern basically without what. And this price follows cost of research and development concern basically without what..
Angell still was analysed at that time (2001) medical look forward to is so called " 820 million dollar creates a new drug " crammer, think medicaments develops Dafute the research center is a chain of the result of fallacybrass faucet aerator , do not have basis of how many fact. "I estimate, the real cost of medicaments of avery kind of is average under 100 million dollar. If it is the word that approachs 820 million dollar really, pharmacy line of business also won't is opposite concerned data closely guard a secret. Pharmacy line of business also won't is opposite concerned data closely guard a secret..
She discovers, a lot of cost of medical look forward to spend the sale promotion that oppugns in your person to go up. With respect to Lan Su resembling arrowroot Shi Ke does in that way, and be not medicaments of truly beautiful ongoing hair, innovation to go up.
Additional, angell thinks, medical look forward to exaggerated the company innovates in medicaments the action in the process. Very much new drug is discovered by the research organization such as the university first, give medicine look forward to patent permission next, undertake clinical trial is pushed again to the market.
The United States nots auspicious Ni Yada learns to study vice-president holds innovation concurrently to carry out trustee mark·When Kelaoweier was answering a reporter to quiz recently also confirm Angell's view. Kelaoweier says, "Be in university of respect of new drug research and development is engine, can saying even is fuel " .
"2006, american university established enterprise of many 500 newly established, among them 2/3 lies biology medicine course of study. Additional, enterprise of newly established of American biology medicine has 2/3 to be university institute activate. Did not have an university, the ecosystem of mthe most popular norton internet antivirusedical research and development or industrial catenary is half-baked, and a lot of new drug of those big now medicine look forward to also are to rely on to cooperate to come with other orgnaizations, for example from university newly established buy over there the enterprise. " he says.
If install Jill and Kelaoweier to say is a fact, so the public buried sheet twice for medicaments.
Open black box
Recently, national hair changes appoint launch cost investigation to partial medicine look forward to, involve 60 well-known companies, include Ansitai to come among them, the transnational corporation such as Shi Ke of Ge Lan element. National hair changes appoint express, the purpose that investigates this depends on understand and mastering pull current of medicines and chemical reagents to pass the cost in Cheng, price to reach concerned situation, make in time adjust drug price.
In fact, it is policy constitutor not only, social all circles feels, medical look forward to needs a few diaphaneity pressingly now. People needs to know, how much did pharmacy company cost on research development after all, and when once medicaments filed patent,entering clinical experiment, staff of research and development ran where to go again; People needs to know, in clinical before level, clinical phase and market research phase spent how many money; People needs to know more, how does the operation cost of a huge sum produce, what is the pocket that runs to doctor, official. . . . . . Without these information, people also does not understand high medical price forever was to encourage innovation or develop deceit.
To China, this on one hand meaning especially important. Current, besides the state that abandons industrial pursuit individually, world each country is faced with the contradiction of total cost of development pharmacy line of business and control sanitation. Wanting the key that resolves these contradiction is the efficiency that improves pharmacy trade, using Qian Zhen on the redound that innovate and innovates. For this, chinese government changes drug price to cost the means of addition entirely gradually, allow reasonable profit on product cost basis namely. This is originally take care of supply and demand the plan of the demand perfection of two end. But, the cost of medicaments relies on enterprise ego to declare. The personage inside course of study expresses, a few moment, how is the cost that the government feels look forward to of not clear medicine at all made, it is to rely on an enterprise to say to oneself completely, accordingly, a lot of prices also are accomplished hard reasonable, have the effect of incentive innovation very hard also truly.
Angell says, medicaments price wants not only transparent, and want reasonable, and be united to all purchaser as far as possible. The state that this kind of person that lets least pay ability pays maximum price now is inequitable. Ought to have certain control to the price. Although lower the price significantly, the gain of pharmacy line of business is potential still very tall, if it can decrease,spread the word of defray especially. As a result of prescription drug the biggest purchaser is a government, it can have price negotiation and control on behalf of everybody.
Chinese government has realized the problem is in and take action actively. Promulgate recently " deepen medical sanitation system to reform main 2013 job to arrange " in emphasize, should " perfect drug price runs policy, form of innovation government price and method " . Among them special mention should " in investigating purchase and sale of medicines and chemical reagents stoutly dark buckle behavior " . It is current that this ases if large-scale try to find out the real intention the investigation, operation that increases superintendency strength is enunciative.
The effect is apparent. After be investigated, element history overcomes Ge Lan to had announced, the plan is passed adjust operation pattern, reduce the operation cost in drug price, the medicines and chemical reagents of the company of Shi Ke of arrowroot orchid element that allows more China patient to acquire high quality thereby.
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